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Original articles 2016

The most visible original articles of the year with first or last authors from the medical faculty (without reviews, letters, case reports, comments or news).

Dreyling M1, Jurczak W, Jerkeman M, Silva RS, Rusconi C, Trneny M, Offner F, Caballero D, Joao C, ..., Rule S
Ibrutinib versus temsirolimus in patients with relapsed or refractory mantle-cell lymphoma: an international, randomised, open-label, phase 3 study.
Lancet 2016; 387: 770-8 (JIF2015 44,0)
1 Medizinische Klinik und Poliklinik III

Kroidl I1, Saathoff E1, Maganga L, Makunde WH, Hoerauf A, Geldmacher C1, Clowes P, Maboko L, Hoelscher M1
Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study.
Lancet 2016; 388: 1912-1920 (JIF2015 44,0)
1 Abteilung für Infektions- und Tropenmedizin

Hou L, Heilbronner U1, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, ..., Falkai P2, …, Schulze TG1
Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
Lancet 2016; 387: 1085-93 (JIF2015 44,0)
1 Institut für Psychiatrische Phänomik und Genomik
2 Klinik und Poliklinik für Psychiatrie und Psychotherapie

Villa R1, Schauer T1, Smialowski P1, Straub T1, Becker PB1
PionX sites mark the X chromosome for dosage compensation.
Nature 2016; 537: 244-248 (JIF2015 38,1)
1 Biomedizinisches Centrum München (BMC)

Schmidt K, Worrack S, Von Korff M, Davydow D, Brunkhorst F, Ehlert U, Pausch C, Mehlhorn J, Schneider N, ..., Schelling G1
Effect of a primary care management intervention on mental health-related quality of life among survivors of sepsis: a randomized clinical trial.
JAMA 2016; 315: 2703-11 (JIF2015 37,7)
1 Klinik für Anästhesiologie

Krietenstein N1, Wal M, Watanabe S, Park B, Peterson CL, Pugh BF, Korber P1
Genomic nucleosome organization reconstituted with pure proteins.
Cell 2016; 167: 709-721.e12 (JIF2015 28,7)
1 Biomedizinisches Centrum München (BMC)

Harbeck N1, Huang CS, Hurvitz S, Yeh DC, Shao Z, Im SA, Jung KH, Shen K, Ro J, ..., LUX-Breast 1 study group
Afatinib plus vinorelbine versus trastuzumab plus vinorelbine in patients with HER2-overexpressing metastatic breast cancer who had progressed on one previous trastuzumab treatment (LUX-Breast 1): an open-label, randomised, phase 3 trial.
Lancet Oncol 2016; 17: 357-66 (JIF2015 26,5)
1 Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe

Stintzing S1, Modest DP1, Rossius L1, Lerch MM, von Weikersthal LF, Decker T, Kiani A, Vehling-Kaiser U, Al-Batran SE, ..., FIRE-3 investigators
FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab for metastatic colorectal cancer (FIRE-3): a post-hoc analysis of tumour dynamics in the final RAS wild-type subgroup of this randomised open-label phase 3 trial.
Lancet Oncol 2016; 17: 1426-1434 (JIF2015 26,5)
1 Medizinische Klinik und Poliklinik III

Pan C1, Cai R1, Quacquarelli FP1, Ghasemigharagoz A1, Lourbopoulos A1, Matryba P1, Plesnila N1, Dichgans M1, Hellal F1, Ertürk A1
Shrinkage-mediated imaging of entire organs and organisms using uDISCO.
Nat Methods 2016; 13: 859-67 (JIF2015 25,3)
1 Institut für Schlaganfall- und Demenzforschung

Al-Shahi Salman R, McGoohan K, Rodrigues M, Dichgans M1
Dementia after stroke due to intracerebral haemorrhage.
Lancet Neurol 2016; 15: 779-80 (JIF2015 23,5)
1 Institut für Schlaganfall- und Demenzforschung

Gascón S1, Murenu E1, Masserdotti G1, Ortega F1, Russo GL1, Petrik D1, Deshpande A1, Heinrich C1, Karow M1, ..., Götz M1
Identification and successful negotiation of a metabolic checkpoint in direct neuronal reprogramming.
Cell Stem Cell 2016; 18: 396-409 (JIF2015 22,4)
1 Biomedizinisches Centrum München (BMC)

Westphalen CB1, Takemoto Y, Tanaka T, Macchini M, Jiang Z, Renz BW2, Chen X, Ormanns S3, Nagar K, ..., Wang TC
Dclk1 defines quiescent pancreatic progenitors that promote injury-induced regeneration and tumorigenesis.
Cell Stem Cell 2016; 18: 441-55 (JIF2015 22,4)
1 Medizinische Klinik und Poliklinik III
2 Klinik für Allgemein-, Viszeral-, Gefäß- und Transplantationschirurgie
3 Pathologisches Institut

Gluz O, Nitz UA, Christgen M, Kates RE, Shak S, Clemens M, Kraemer S, Aktas B, Kuemmel S, ..., Harbeck N1
West German Study Group Phase III PlanB Trial: First prospective outcome data for the 21-gene recurrence score assay and concordance of prognostic markers by central and local pathology assessment.
J Clin Oncol 2016; 34: 2341-9 (JIF2015 21,0)
1 Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe

Hoster E1, Rosenwald A, Berger F, Bernd HW, Hartmann S, Loddenkemper C, Barth TF, Brousse N, Pileri S, ..., Klapper W
Prognostic value of Ki-67 index, cytology, and growth pattern in mantle-cell lymphoma: Results from randomized trials of the European Mantle Cell Lymphoma Network.
J Clin Oncol 2016; 34: 1386-94 (JIF2015 21,0)
1 Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie