ERC Advanced Grant - Microbiome-derived asthma and allergy protective substances for prevention
- Project leader: Prof. Dr. Dr. h.c. Erika von Mutius
- Affiliation: Department of Pediatric Surgery, Dr. von Hauner Children’s Hospital
- Funding: 2023 to 2027
Project description:
Asthma affects both children and adults. However, it is the most common chronic disease among children. It is estimated that one in 10 school-age children suffer from asthma. Allergies are also very prevalent, with up to 50 % of children being diagnosed with them. Unfortunately, there is no cure or effective prevention available. The ERC-funded APROSUS project will advance the field of microbiome research towards in-depth characterisation of microbe-derived metabolite complexes to better understand their associated asthma and allergy protective properties. Project work will be based on previous studies carried out by the team, whereby both asthma and allergies were explored together, identifying relevant taxa of the environmental microbiome and discovering microbiome-derived functional agents conferring protection.