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BMBF-Network TB-Sequel: Concomitant diseases, risk factors and long-term complications that define the individual therapeutic success of tuberculosis and its impact on public health.

  • Coordinator: Dr. Gavin Churchyard, Südafrika
  • German contact person: Prof. Dr. Michael Hoelscher
  • Affiliation: Division of Infectious Diseases and Tropical Medicine, University Hospital, LMU Munich
  • Participating countries: Tansania, Mozambique, Gambia, South Africa
  • Funding by BMBF: 2016 to 2021

The African continent today is emblematic of tuberculosis (TB) as a global health emergency with little known about the long-term sequelae. There is cumulative evidence for prolonged pulmonary morbidity and loss of longevity in former TB patients. It is likely that TB patients from resource-constrained settings, who usually present with more extensive disease, are left with substantial and chronic lung impairment.

This project aims:

  • to advance the understanding of the clinical, microbiologic, environmental and host immune factors affecting the long-term sequelae of pulmonary TB;
  • to determine occurrence of reversible and irreversible costs and socioeconomic consequences for TB patients and health care systems;
  • and to facilitate novel interventions to restore and preserve overall health, well-being and financial protection in patients with TB.

Source: TB Sequel