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Top Publications of Faculty of Medicine 2017, JIF > 20

Ruzicka T1, Hanifin JM, Furue M, Pulka G, Mlynarczyk I, Wollenberg A1, Galus R, Etoh T, Mihara R, ..., Zebrowska A
Anti-Interleukin-31 receptor A antibody for atopic dermatitis.
N Engl J Med 2017; 376: 826-835 (JIF2016 72,4)
1 Department of Dermatology and Allergy

Marcus R, Davies A, Ando K, Klapper W, Opat S, Owen C, Phillips E, Sangha R, Schlag R, ...,Hiddemann W1
Obinutuzumab for the first-line treatment of follicular lymphoma.
N Engl J Med 2017; 377: 1331-1344 (JIF2016 72,4)
1 Department of Medicine III

Alberer M1, Gnad-Vogt U, Hong HS, Mehr KT, Backert L, Finak G, Gottardo R, Bica MA, Garofano A, ..., von Sonnenburg F1
Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial.
Lancet 2017; 390: 1511-1520 (JIF2016 47,8)
1 Division of Infectious Diseases and Tropical Medicine

Sibbing D1, Aradi D, Jacobshagen C, Gross L1, Trenk D, Geisler T, Orban M1, Hadamitzky M, Merkely B, ..., Rasp O
Guided de-escalation of antiplatelet treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention (TROPICAL-ACS): a randomised, open-label, multicentre trial.
Lancet 2017; 390: 1747-1757 (JIF2016 47,8)
1 Department of Medicine I

Gaertner F1, Ahmad Z1, Rosenberger G1, Fan S1, Nicolai L1, Busch B2, Yavuz G, Luckner M, Ishikawa-Ankerhold H1, ..., Massberg S1
Migrating platelets are mechano-scavengers that collect and bundle bacteria.
Cell 2017; 171: 1368-1382.e23 (JIF2016 30,4)
1 Department of Medicine I
2 Max von Pettenkofer Institute

Izawa T, Park SH, Zhao L, Hartl FU, Neupert W1
Cytosolic protein Vms1 links ribosome quality control to mitochondrial and cellular homeostasis.
Cell 2017; 171: 890-903.e18 (JIF2016 30,4)
1 Biomedical Center (BMC)

Witzel M1, Petersheim D1, Fan Y1, Bahrami E1, Racek T1, Rohlfs M1, Puchałka J1, Mertes C, Gagneur J, ..., Klein C1
Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes.
Nat Genet 2017; 49: 742-752 (JIF2016 28,0)
1 Department of Pediatrics, Dr. von Hauner Children’s Hospital

Bertini E, Dessaud E, Mercuri E, Muntoni F, Kirschner J, Reid C, Lusakowska A, Comi GP, Cuisset JM, ..., Walter MC1
Safety and efficacy of olesoxime in patients with type 2 or non-ambulatory type 3 spinal muscular atrophy: a randomised, double-blind, placebo-controlled phase 2 trial.
Lancet Neurol 2017; 16: 513-522 (JIF2016 26,3)
1 Department of Neurology

Harbeck N1, Gluz O, Christgen M, Kates RE, Braun M, Küemmel S, Schumacher C, Potenberg J, Kraemer S, ..., Nitz UA
De-escalation strategies in human epidermal growth factor receptor 2 (HER2)–positive early breast cancer (BC): final analysis of the West German Study Group J
Clin Oncol 2017; 35: 3046-3054 (JIF2016 24,0)
1 Department of Obstetrics and Gynecology

Dreyling M1, Santoro A, Mollica L, Leppä S, Follows GA, Lenz G, Kim WS, Nagler A, Panayiotidis P, ..., Zinzani PL
Phosphatidylinositol 3-Kinase Inhibition by copanlisib in relapsed or refractory indolent lymphoma.
J Clin Oncol 2017; 35: 3898-3905 (JIF2016 24,0)
1 Department of Medicine III

Druzd D1, Matveeva O, Ince L1, Harrison U2, He W, Schmal C, Herzel H, Tsang AH, Kawakami N3, ..., Scheiermann C1
Lymphocyte circadian clocks control lymph node trafficking and adaptive immune responses.
Immunity 2017; 46: 120-132 (JIF2016 22,8)
1 Department of Dermatology and Allergy
2 Max von Pettenkofer Institute
3 Institute of Clinical Neuroimmunology

Essig K1, Hu D1, Guimaraes JC, Alterauge D1, Edelmann S, Raj T1, Kranich J1, Behrens G1, Heiseke A1, ..., Heissmeyer V1
Roquin suppresses the PI3K-mTOR signaling pathway to inhibit T helper cell differentiation and conversion of Treg to Tfr cells.
Immunity 2017; 47: 1067-1082.e12 (JIF2016 22,8)
1 Institute for Immunology

Duchene J1, Novitzky-Basso I, Thiriot A, Casanova-Acebes M, Bianchini M1, Etheridge SL, Hub E, Nitz K, Artinger K, ..., Rot A1
Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis.
Nat Immunol 2017; 18: 753-761 (JIF2016 21,5)
1 Institute of Cardiovascular Prevention